Noida, India — 15 January, 2026 – Ikris Pharma Network announced the availability of Triokris™ (Trientine Dihydrochloride 250 mg Capsules), a therapeutic option for patients diagnosed with Wilson’s Disease, a rare inherited disorder of copper metabolism. Triokris is designed to support clinicians in the management of patients requiring chelation therapy, especially in cases where first-line agents are contraindicated or not tolerated.

Wilson’s Disease is a progressive condition that, if untreated, can lead to severe hepatic, neurological, and psychiatric complications due to toxic copper accumulation. Early diagnosis and long-term treatment are critical for achieving meaningful clinical outcomes.

Triokris (Trientine Dihydrochloride) is recognized internationally as a well-established chelating agent with a long-standing clinical history. It is widely used across the United States, Europe, India, and multiple global regions for the management of Wilson’s Disease. The formulation is known for its stability profile and predictable absorption characteristics.

Intended Audience Notice: This announcement is intended for healthcare professionals, hospitals, and authorized importers involved in the treatment and management of Wilson’s disease.

Key Highlights:

  • Triokris™ (Trientine Dihydrochloride 250 mg) is now available via Named Patient import pathways
  • Supports patients with Wilson’s disease who are intolerant to first-line therapy
  • Supplied under full regulatory compliance with complete quality documentation
  • Backed by GDP-aligned global logistics and pharmacovigilance oversight

Commitment to Rare Disease Care

Addressing the importance of patient access, Mr. Praveen Sikri, Founder & CEO, and Mr. Bharat Sikri, Director of Ikris Pharma Network, stated:

“Our focus has always been on supporting physicians and hospitals managing complex and rare conditions. With Triokris, we are helping enable access to a globally trusted chelation therapy for patients living with Wilson’s Disease, through compliant and well-structured pathways.”

Through its global sourcing network and regulatory-compliant import pathways, Ikris Pharma Network facilitates access to essential therapies in alignment with the Drugs & Cosmetics Act, ensuring product authenticity, full documentation, and cold-chain integrity where required.

About Triokris™ (Trientine Dihydrochloride)

Triokris is an oral chelating agent used for the removal of excess copper from the body. It is typically considered in:

  • Patients with intolerance to D-Penicillamine
  • Patients requiring maintenance therapy
  • Clinical scenarios where a stable, predictable chelator is preferred

The formulation consists of 250 mg of Trientine Dihydrochloride, developed to meet internationally accepted quality standards. Triokris is not intended to replace the clinical judgment of healthcare professionals, and treatment decisions should always be guided by a physician experienced in managing Wilson’s Disease.

Strengthening Access Through Regulatory Compliance

Ikris Pharma Network operates under strict adherence to Indian regulatory frameworks, ensuring that medicines supplied under the Named Patient Import Program follow mandated approval processes, documentation, batch traceability, and patient safety safeguards.

The organization collaborates with global manufacturers and GDP-compliant logistics partners to maintain integrity from dispatch to delivery. Each supply is backed by relevant quality documents.

A Step Forward for the Wilson’s Disease Community

The introduction of Triokris underscores Ikris Pharma Network’s mission to improve treatment access for underserved patient populations. The company continues to work closely with hepatologists, neurologists, rare disease centers, and patient support groups to strengthen awareness and early management of Wilson’s Disease.

About Ikris Pharma Network

Ikris Pharma Network is a global pharmaceutical services organization specializing in Named Patient Access, Rare Disease Medicines, Generic Medicine Export, RLD/Comparator Drug Supply, and Clinical Trial Support. The company partners with hospitals, physicians, and leading pharmaceutical manufacturers across the world to enable compliant access to hard-to-find therapies worldwide.

The company operates from its global headquarters in India and has established offices in Belgium, Bulgaria, and Hong Kong, supported by two strategic pharmaceutical warehouses in Europe. Ikris ensures end-to-end regulatory compliance, GDP-aligned supply-chain operations, and robust pharmacovigilance practices across all markets it serves.

Safety Reporting Information:

For any suspected adverse events or side effects associated with the use of Triokris™, healthcare professionals and patients are encouraged to report them by contacting drugsafety@ikrispharmanetwork.com.

Reporting safety information supports ongoing pharmacovigilance activities and helps ensure the continued safe and appropriate use of the medicine.

Disclaimer:

This material is provided for informational purposes only. Triokris™ is supplied in accordance with applicable regulatory requirements. Treatment decisions must be made by qualified healthcare professionals based on individual patient needs.

Media Contact:

Ikris Pharma Network Pvt. Ltd.
Email:
info@ikrispharmanetwork.com
Website: www.ikrispharmanetwork.com
TOLL-FREE: 1800 1200 365

London [UK], November 26: The World Leadership Forum successfully delivered a landmark international programme from 19th to 23rd November 2025, culminating in the prestigious International Conclave 2025 held at the iconic UK Parliament. The multi-day series brought together influential delegates, policymakers, innovators, and cultural leaders from India, the UK, and around the globe to advance dialogue on leadership, sustainability, global cooperation, and the vision of Viksit Bharat.

“Hosting this Conclave in the heart of the UK’s democracy underscores the critical importance of the India-UK partnership in shaping a prosperous, sustainable global future,” said Mr. Nachiket Joshi (Founder, World Leadership Forum), whose vision and commitment made the initiative possible. “This initiative connects global leadership networks to support the mission of Viksit Bharat and cultivate meaningful, lasting partnerships.”

The programme opened with a spiritual and cultural gathering at the BAPS Swaminarayan Temple, where delegates participated in an uplifting aarti ceremony followed by a warm prasad that fostered unity and cross-cultural goodwill. The entire programme was marked by the exceptional leadership of Mr. Nachiket Joshi (Founder, World Leadership Forum) and the impeccable coordination of Khushboo Shah (Organiser & Professional from UK), whose combined vision, dedication, and execution ensured the success and prestige of the international gathering.

The Conclave was supported by the partnership of the Wey Foundation, Mumbai, represented by Shirin Aggarwal, and Hirdesh Gupta from IDUK. Their involvement contributed to the collaborative efforts that helped ensure the event’s smooth execution and its broader aim of encouraging meaningful India-UK engagement.

The House of Commons session, hosted by MP Joy Morrissey (MP for Beaconsfield), focused on expanding bilateral cooperation in areas such as trade, education, healthcare, investment, and sustainable development. Dignitaries present included MP Jack Rankin (Member of Parliament, Windsor), former MP Virendra Sharma (Former Member of Parliament, UK), Srimathi Shivashankar (Vice President, HCL), Suhel Seth (Author, Columnist & Brand Strategist), Vijay Goel (Founder, India European Business Forum), Dr. Bharat Pankhania (Mayor of Bath), Cllr Anjana Patel (Mayor of Harrow), Khushboo Shah (Organiser), Swami Chakrapani Maharaj (National President, Hindu Mahasabha), Sandeep Goenka (Founder, C.P. Goenka International School), Hirdesh Gupta (Founder, IDUK), Shirin Aggarwal (Founder, Wey Foundation Mumbai), Shipra Pathak (Water Woman of India), and Rupal Dalal (Managing Director, JD Fashion Institute, India).

The parliamentary engagements continued at the House of Lords, where Lord Sahota (Life Peer) hosted an elegant afternoon reception attended by esteemed leaders including Lord Rami Ranger (Life Peer & Business Leader), who were recognised for their contributions to leadership and India-UK collaboration.

Additional influential delegates included, Abhey Bansal (Chairperson, AB Group), Shyna Sunsara (Model, Actor & Co-Producer at AB Bansal productions), Yogita Bhayana (Social Activist & NGO Founder), Neha Singh (Government of Maharashtra Representative), Lokesh Kumar (BJP Leader, Andhra Pradesh), Vinita Gupta (Technology Entrepreneur, Silicon Valley), Sanjay Gupta (Former President, The Cost Accountants of India), Chinu Kwatra (Founder, Khushiyaan Foundation), Hussain Ahmedali Nalwala (Philanthropist, Nalwala Foundation), Tarun Ghulati (Businessman & Investment Banker), Sanjay Thakkar (Sr. Advisor & Investor), Loveena Tandon (Journalist, Foreign correspondent, Aaj Tak & India Today) and Rabih El Fadel (CEO, Phyla Earth).

Beyond Westminster, the delegation engaged in meaningful community and leadership interactions. An impactful engagement was held in the Mayor’s Parlour in Harrow, led by Cllr Anjana Patel (Mayor of Harrow), where discussions centred on Indo-UK community partnerships and collaborative social initiatives. The programme also celebrated India’s creative and cultural strength at India Fashion Week London, where delegates attended a vibrant fashion show showcasing Indian craftsmanship and global design influence.

The series concluded in the historic city of Bath, where the delegation was warmly hosted by Cllr Dr. Bharat Pankhania (Mayor of Bath). The visit deepened cultural understanding and explored collaboration in governance, heritage preservation, and community development.

Reflecting on the programme’s success, Khushboo Shah shared:

“It has been an honour to bring together such an extraordinary group of leaders across cultural spaces, community platforms, and the UK Parliament. This series stands as a testament to what shared purpose, collaboration, and global friendship can achieve. I am deeply grateful to every dignitary who contributed to meaningful dialogue that bridges nations and inspires future progress.”

The International Conclave 2025 reaffirmed the Forum’s commitment to bringing forward-thinking leaders together to build a more collaborative, sustainable, and progressive global future. Discussions underscored India’s aspiration to become a developed nation by 2047, highlighting innovation, inclusive growth, strong governance, and international partnerships.

About The World Leadership Forum

The World Leadership Forum is a global platform dedicated to fostering cross-border cooperation, sustainable development, and leadership excellence. Through high-impact convenings, the Forum facilitates meaningful discussions on diplomacy, socio-economic progress, and ethical leadership to drive positive global change.

From regular exercise to eating well, there are many things you can do to protect your joints. Try these tips for healthy knees and maintaining joint health.

One of the largest and most complex joints of the body, the knee is crucial to movement, which means protecting knee joints should be a priority. Our knees make it possible for us to walk, jump, dance, pedal a bicycle, climb steps or ladders, kick balls or tires, squat to sit, or bend to lift a child – all while bearing the weight of our bodies.

The knee is also one of the joints most prone to pain, injury and many forms of arthritis. If we live long enough, most will experience knee problems at some point. But there are ways to minimize the impact of knee problems. Dr. Gaurav Gupta from Jhansi, who is a Knee Pain specialist says “Practicing a healthy lifestyle and good posture can help in preventing the development of age-related arthritis as well as slow down its progression”

Try these tips for healthy knees.

1. Get moving. Your joints were designed for movement. Regular physical activity can help your knees and other joints in relieving pain and stiffness, strengthening the muscles that provide support to the knees, reducing weight gain that puts excess stress on knees, improving balance to decrease your risk of falls and injuries to the knees and other joints.

It’s important to pick exercises that are gentle and safe to decrease your risk of joint injury and to try a combination of activities that promote flexibility and range of motion (such as yoga or exercises prescribed by a physical therapist), muscle strengthening (such as working out with weight machines or resistance bands), or cardiovascular fitness (such as walking, swimming or bicycling). Physical therapy for knee arthritis can help keep your knees functioning at their best.

2. Maintain a healthy weight. If you are overweight, every excess kilogram puts additional stress on your knees that can increase cartilage wear and tear thus leading to pain. many patients Research shows that for people with osteoarthritis (OA) of the knee, losing even a little bit weight can help make a huge difference.

Although it makes sense that excess weight can be harmful to knees — which bear the body’s weight — the weight-joint connection is more complex than just the mechanical forces extra weight put on the knees. Fat itself produces and releases chemicals that promote inflammation. Thus, excess fat is associated not only with OA, but with various forms of arthritis involving inflammation, including rheumatoid arthritis, psoriatic arthritis and gout, all of which can cause joint damage.

Maintaining a healthy weight may be one of the best things you can do for keeping your joints healthy. Dr. Gaurav Gupta, who has his own Orthopedic practice in Jhansi, always advices patient’s with knee pain to keep their weight in check, and in his experience, if a patient with knee pain loses even 3-5 kg excess body weight, their knee pain actually disappears.

3. Protect knees from injury. Injury to an arthritic knee can cause further damage to the joint. Injury to a healthy knee may lead to arthritis down the road.

To protect your knees, avoid activities that involve repetitive pounding such as jogging or high-impact aerobics. If u a play sports that involve pivoting or contact such as basketball or football, a doing a proper warm-up and training is essential to prevent the risk of injury. “Listen to your body — if you experience pain in a joint or joints, rest for a while”, says Dr. Gupta.

To reduce your risk of injury while lifting or carrying something heavy, use your largest, strongest joints and muscles to take stress off smaller hand joints and to spread the load over large surface areas. Hold items close to your body, which is less stressful for your joints. For joint safety, slide objects whenever possible rather than lifting them.

In some cases, wearing a knee brace during certain activities may be helpful in preventing injury, although the evidence to support the use of braces for that purpose is not conclusive. A physical therapist can help you determine if a brace — and, if so, which one — is right for you.

4. Treat injuries promptly. If you do injure a knee or other joint, reduce swelling and promote healing by practicing P.O.L.I.C.E. (PROTECTION, OPTIMAL LOADING, ICE, COMPRESSION AND ELEVATION)

Rest your knees and avoid activities that cause pain.

Place a cold pack or bag or ice wrapped in a towel on the painful knee for 20 minutes at a time several times a day.

Wrap an elastic bandage securely around the injured knee to reduce swelling.

Recline with your leg placed on a pillow to keep your knee elevated above your heart as often as you can.

If your pain is severe, you can’t bend or bear weight on your knee or pain doesn’t improve after a few days, speak with your doctor.

5. Pay attention to pain. If you experience new or worsened pain in a joint or joints, it’s important to speak with your doctor. Pain can be a sign of injury or increased disease activity, both of which may require treatment to prevent further damage to your joint(s). If arthritic knee pain, keeps you from being active, it’s a threat to your joints’ health. For that reason, it’s important to talk to your doctor and find pain treatments that work for you. Dr. Gaurav Gupta, points out that patients with knee pain who consult him at the right time, and start with conservative treatments like medications, nutritional supplements, hot and cold therapy, exercises and choose healthy lifestyle may never need knee surgery. So, do not neglect any persistent joint pain.

6. Avoid Smoking. If you smoke, add joint health to yet another reason to quit. For almost two decades’ research has connected smoking with more severe pain and joint damage in both osteoarthritis and rheumatoid arthritis.

7. Eat a healthy diet. A diet rich in fruits, vegetables, fish, nuts and beans and low in processed foods and saturated fats can not only reduce your risk of cardiovascular and other diseases of aging, but it may also promote healthy joints. Also, minimize your consumption of carbonated soft drinks, coffee and alcohol, which can increase excretion of calcium from the body and affect your bone health.

8. Practice good posture. Over time, bad posture can place abnormal stresses on your joints, leading to excess cartilage wear and damage. Consistently practicing good posture decreases those stresses by allowing your muscles to work more effectively to support the joints. To practice good posture, stand with up straight with your shoulders back, head level and in line with your body, abdomen tucked in and feet shoulder-width apart. When sitting, keep your back against the back of the chair, your feet flat on the floor, a small space between the backs of your knees and the chair, and your knees at the same height or slightly lower than your hips. A physical therapist can teach you exercises to improve your posture. A physical or occupational therapist can also help you arrange your workspace to improve posture and relieve joint stress on the job.

9. Take care in selecting footwear. Dr. Gupta says, “The wrong shoes can not only hurt the joints in your feet, but they can also throw off your posture and affect joints all the way up your body”. High heels, for example, put extra stress on your knees and may increase your risk of developing osteoarthritis. For your joints’ sake, choose shoes with a low or no heel. Look for flexible, supportive shoes with a square or rounded toe that allows your toes to move around. Look for shoes that are well cushioned and flexible at the ball of the foot, where you push off, but supportive enough that you cannot bend it in half from heel to toe. For foot or knee pain consider a shoe insert or orthotic support. A physical therapist can recommend the best one for you.

10. Be good to your bones. Your joints can’t be healthy if the bones that join to form them aren’t. Many of the habits you practice to help your joints — regular exercise, a healthy diet — are also essential for strong bones. For bone health, ensure that your diet is high in calcium and vitamin D (naturally available in tuna, salmon, swordfish, egg yolks as well as in fortified milk, juices and cereals). If you aren’t sure you’re getting enough, speak with your doctor about supplements.

Visit us on www.docgauravgupta.com/ www.joh.co.in

Radiqle Systems, Inc., a leading technology company based in USA, is excited to announce a strategic investment in Curetek Health Innovations, a Bangalore-based AI start-up specializing in developing advanced algorithms for healthcare diagnostics. This partnership marks a significant step forward in the global expansion of AI-driven solutions aimed at transforming healthcare diagnostics and improving patient outcomes worldwide.

Curetek Health Innovations Pvt. Ltd. has assembled a team of professionals with extensive experience in technology-enabled healthcare. The company’s mission is to lead the integration of artificial intelligence and machine learning in healthcare, with a specific focus on medical diagnostics. Its advanced algorithms will analyze medical imaging, patient data, and lab results to assist healthcare professionals in making faster, more accurate diagnoses, thereby improving early disease detection and enhancing overall treatment efficiency.

Radiqle has pledged a $1M investment to support Curetek in scaling its AI-driven diagnostic platform. This funding will help enhance Curetek’s research and development efforts and broaden its reach in both the Indian and global markets. The collaboration will also expedite the adoption of AI technology in essential healthcare systems, addressing the increasing demand for faster and more accurate diagnostics.

“We are thrilled to invest in Curetek, a company that will be leading the way in AI-powered healthcare diagnostics,” said Anirban Das, President of Radiqle Systems. “The team at Curetek has demonstrated exceptional expertise in both AI technology and healthcare, and we believe their solutions have the potential to transform the medical field, improving accuracy and efficiency in diagnosing a wide range of diseases. This collaboration aligns with our long-term vision of supporting the global healthcare ecosystem with cutting-edge technological advancements.”

Somenath Chatterjee, Founder and CEO of Curetek, added: “We are excited to welcome Radiqle Systems as a strategic partner. This investment will enable us to accelerate the development of our AI diagnostic solutions and expand our reach into new markets. By leveraging AI, we aim to revolutionize healthcare diagnostics and provide doctors with the tools they need to make informed, timely decisions, ultimately improving patient care and saving lives.”

The partnership will also enable Curetek to leverage the expertise and resources of Radiqle Systems, which has a proven track record of scaling emerging technologies on a global scale. The collaboration promises to deliver high-quality AI diagnostic tools to healthcare providers, contributing to better clinical outcomes, reducing diagnostic errors, and lowering healthcare costs.

About Radiqle Systems:

Radiqle Systems is a technology leader specializing in innovative solutions that drive positive change across various industries. With a focus on artificial intelligence, machine learning, and data-driven technologies, Radiqle Systems, has been at the forefront of transforming business landscapes worldwide. Through strategic partnerships and investments, the company continues to push the boundaries of technological innovation to create a smarter, healthier, and more connected world.

About Curetek Health Innovations:

Curetek is an AI technology company based in India, dedicated to revolutionizing healthcare diagnostics through advanced artificial intelligence and machine learning algorithms. The company’s platform is designed to improve diagnostic accuracy, speed up disease detection, and support healthcare professionals in making informed decisions. With a focus on early diagnosis and efficient treatment, Curetek is committed to making healthcare more accessible, effective, and patient-centered across the globe.

For media inquiries, please contact: info@radiqle.com or info@curetekai.com

Websites

www.Radiqle.com | www.CureTekAI.com